{"id":6981,"date":"2023-11-15T10:06:26","date_gmt":"2023-11-15T18:06:26","guid":{"rendered":"https:\/\/stocan.org\/?p=6981"},"modified":"2023-11-15T10:07:33","modified_gmt":"2023-11-15T18:07:33","slug":"taking-charge-of-my-health-with-a-cdh1-gene-mutation-priscilla-brittines-story","status":"publish","type":"post","link":"https:\/\/stocan.org\/taking-charge-of-my-health-with-a-cdh1-gene-mutation-priscilla-brittines-story\/","title":{"rendered":"Taking Charge of My Health With a CDH1 Gene Mutation: Priscilla Brittine&#8217;s Story"},"content":{"rendered":"<p><i><span style=\"font-weight: 400;\">Priscilla Brittine from Kansas made the brave decision to undergo a total gastrectomy and a double mastectomy. As an individual with a CDH1 gene mutation, she faced an increased risk of several cancers, including stomach and breast cancer. This is her story of hope.\u00a0<\/span><\/i><\/p>\n<p>&nbsp;<\/p>\n<p><iframe title=\"Taking Charge of My Health With a CDH1 Gene Mutation: Priscilla Brittine&#039;s Story\" width=\"1200\" height=\"675\" src=\"https:\/\/www.youtube.com\/embed\/t3Sky5nxRFA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" allowfullscreen><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">At the age of 14, I watched my mom suffer from stomach cancer. She had an aggressive type that caused her to pass away in her early 40s. She was gone less than a year after getting her diagnosis &#8211; and much too soon. Leading up to that time, she was misdiagnosed, put off, and not taken seriously. Thankfully, we learned one thing from her experience: my mom had a <a href=\"https:\/\/www.mskcc.org\/news\/6-things-know-about-cdh1-gene-mutation-and-stomach\">CDH1 gene mutation<\/a>, a trait that can impact multiple people in the same family.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-medium wp-image-6984 alignleft\" src=\"https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-300x296.jpg\" alt=\"CDH1-gene\" width=\"300\" height=\"296\" srcset=\"https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-300x296.jpg 300w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-1024x1010.jpg 1024w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-768x757.jpg 768w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-600x592.jpg 600w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291-65x65.jpg 65w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_123650291.jpg 1170w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>Our Family History with the CDH1 Gene Mutation<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Having a CDH1 gene mutation greatly increases your risk of having stomach, breast, colorectal, thyroid, or ovarian cancer. In particular, it causes an aggressive form of stomach cancer called hereditary diffuse gastric cancer. In women, there is a high risk of developing lobular breast cancer, as well. People with a family history of stomach cancer have a lifetime risk rate of <\/span><a href=\"https:\/\/www.mskcc.org\/news\/6-things-know-about-cdh1-gene-mutation-and-stomach\"><span style=\"font-weight: 400;\">70 percent<\/span><\/a><span style=\"font-weight: 400;\"> for developing stomach cancer, and women with the CDH1 gene mutation have a 56 percent risk of getting lobular breast cancer.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">We saw the effects of the CDH1 gene mutation at work in my family: my mom had cancer, as did her brother (my uncle). At least nine of my cousins have passed away from cancer, and I have four cousins who are living without stomachs since they all opted to have gastrectomies.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Choosing to Safeguard My Future\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Knowing my family history, I had some big decisions to make. I noticed I had some unusual nodes around the time that I got my COVID shots. I was in my early 30s at the time, but since cancer can strike at any age, I\u2019d been monitoring my body closely with scans, mammograms, and regular checkups. Truthfully, it was tiring to live with uncertainty about my future.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">I learned that my insurance would cover prophylactic (preventative) surgery in my case due to the gene mutation. Diagnostic testing didn\u2019t show anything concerning, and I didn\u2019t have any symptoms. However, I elected to have a total gastrectomy in 2019, just to be safe. The surgery went well, and as I was recovering in the hospital, I heard some shocking news: the surgeon had seen early signs of gastric cancer when removing my stomach. They told me I\u2019d had my surgery in the nick of time.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">A Rough Road to Recovery\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The total gastrectomy was one of the hardest experiences I\u2019ve had to endure. I spent a week in the hospital, but my recovery stretched on for months. At home, I had to live with a feeding tube for weeks. I had constant nausea for nearly a year and spent much of my time bed-bound. I had to do physical therapy and found myself in and out of the hospital often. I kept getting thinner and thinner. Further, I\u2019ve had 7 or 8 esophageal dilations. These in-office procedures help stretch the esophagus so that food goes down smoothly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Eventually, I hit a turning point where my condition improved a bit. The nausea and vomiting subsided, and I began to put on a bit of weight. I was grateful for the changes, but I had another big decision to make: I had to think about the future risk of breast cancer.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\"><img decoding=\"async\" class=\"size-medium wp-image-6982 alignright\" src=\"https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-234x300.jpg\" alt=\"CDH1-gene\" width=\"234\" height=\"300\" srcset=\"https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-234x300.jpg 234w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-797x1024.jpg 797w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-768x987.jpg 768w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-1196x1536.jpg 1196w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-1594x2048.jpg 1594w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-600x771.jpg 600w, https:\/\/stocan.org\/wp-content\/uploads\/2023\/10\/image_50456833-scaled.jpg 1993w\" sizes=\"(max-width: 234px) 100vw, 234px\" \/>Deciding to Have a Double Mastectomy\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">I recently decided to have both of my breasts removed to prevent breast cancer in the future. This was a tough surgery as well, and as of October 2023, I\u2019m in the early stages of recovery. It\u2019s difficult to remove parts of your body when you aren\u2019t sure about the future risks &#8211; but I quickly learned that I\u2019d made the right choice after my gastrectomy. Further, I am committed to being here for my children. I don\u2019t want them to live without a mother like I did as a teenager.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the future, I\u2019ll have reconstructive breast surgery. That is the last major procedure I have planned that\u2019s related to my CDH1 gene mutation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">By sharing my story, I hope that I can give others strength and courage &#8211; especially those who are struggling with uncertainty because of their genetics. <\/span><span style=\"font-weight: 400;\">This specific genetic mutation was discovered that year of 2001 (the same year my mom died) in New Zealand. My mom was one of the first, but because of the lack of research back then, she didn&#8217;t have the chance that we had. Basically, it had to take more lives until the door opened for my family with this mutation years later when several of my 2nd generational cousins lost their lives as well. The doctors started questioning what was happening, and that is when we learned the CDH1 mutation in our family. The ones before me who lost their lives paved the way to making this discovery.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This year, I was able to successfully request that the Governor of Kansas give a proclamation to the state regarding CDH1 and stomach cancer risks. That was a major win for me, and I hope others will benefit! <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Priscilla Brittine from Kansas made the brave decision to undergo a total gastrectomy and a double mastectomy. As an individual with a CDH1 gene mutation, she faced an increased risk of several cancers, including stomach and breast cancer. This is her story of hope.\u00a0 &nbsp; At the age of 14, I watched my mom suffer [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":7033,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17,1,13],"tags":[139,123,131,125,133,134,128,129,130,124,127,126,122,141,135,48,137,120,12,138,140,143,132,78,9,121,136,54,142],"hope-story-type":[167,150,158,152,160,161,155,156,157,151,154,153,149,169,162,147,165,144,172,166,168,171,159,145,148,146,163,164,170],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.5 (Yoast SEO v22.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Taking Charge of My Health With a CDH1 Gene Mutation: Priscilla Brittine&#039;s Story &#8226; Hope For Stomach Cancer<\/title>\n<meta name=\"description\" content=\"Priscilla Brittine chose to have a gastrectomy and a double mastectomy because of the CDH1 gene mutation. 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